Emily Monosson

With BPA in baby bottles, mercury in fish, and lead in computer monitors, the world has become a toxic place. But as Emily Monosson demonstrates in her groundbreaking new book, it has always been toxic. When oxygen first developed in Earth's atmosphere, it threatened the very existence of life: now we literally can't live without it. According to Monosson, examining how life adapted to such early threats can teach us a great deal about today's (and tomorrow's) most dangerous contaminants. While the study of evolution has advanced many other sciences, from conservation biology to medicine, the field of toxicology has yet to embrace this critical approach. In Evolution in a Toxic World, Monosson seeks to change that. She traces the development of life's defense systems—the mechanisms that transform, excrete, and stow away potentially harmful chemicals—from more than three billion years ago to today. Beginning with our earliest ancestors' response to ultraviolet radiation, Monosson explores the evolution of chemical defenses such as antioxidants, metal binding proteins, detoxification, and cell death. As we alter the world's chemistry, these defenses often become overwhelmed faster than our bodies can adapt. But studying how our complex internal defense network currently operates, and how it came to be that way, may allow us to predict how it will react to novel and existing chemicals. This understanding could lead to not only better management and preventative measures, but possibly treatment of current diseases. Development of that knowledge starts with this pioneering book.

"Emily Monosson has brought together thirty-four women scientists from over-lapping generations and several fields of research to share their experiences. The authors of the candid essays written for this groundbreaking volume reveal a range of career choices: the authors work part-time and full-time; they opt out and then opt back in; they become entrepreneurs and job share; they teach high school and have achieved tenure. Their stories not only show the many ways in which women can successfully combine motherhood and a career in science but also address and redefine what it means to be a successful scientist." - Provided by publisher

xv, 275 p.

"For more than a century, we have relied on chemical cures to keep our bodies free from disease and our farms free from bugs and weeds. We rarely consider human and agricultural health together, but both are based on the same ecology, and both are being threatened by organisms that have evolved to resist our antibiotics and pesticides. Patients suffer from C.diff, a painful, potentially lethal gut infection associated with multiple rounds of antibiotics; orange groves rot from insect-borne bacteria; and the blight responsible for the Irish potato famine outmaneuvres fungicides. Our chemicals are failing us. Fortunately, scientists are finding new solutions that work with, rather than against, nature. Emily Monosson explores science's most innovative strategies, from high-tech gene editing to the ancient practice of faecal transplants. There are viruses that infect and bust apart bacteria; vaccines engineered to better provoke our natural defences; and insect pheromones that throw crop-destroying moths into a misguided sexual frenzy. Some technologies will ultimately fizzle; others may hold the key to abundant food and unprecedented health. Each represents a growing understanding of how to employ ecology for our own protection. Monosson gives readers a peek into the fascinating and hopeful world of natural defences. Her book is full of optimism, not simply for particular cures, but for a sustainable approach to human welfare that will benefit generations to come."--