Endocrine Therapy in Breast Cancer

This reference evaluates and describes the latest strategies for hormone suppression and blockade in the management of early and advanced stage breast cancer and explores the effects of tamoxifen, selective estrogen receptor modulators (SERMs), aromatase inhibitors, and their combination on both breast cancers and normal tissues.Endocrine Therapy in Breast Cancer details modern techniques for molecular profiling, monitoring, and targetingoffers methods to identify high-risk groups evaluates molecular biomarkers in breast cancer assessmentexamines the potential toxicity of estrogen receptor (ER)-directed endocrine therapyinvestigates the development of endocrine resistancediscusses neoadjuvant and preoperative approaches in patient carereviews mechanisms that lead to estrogen-independent phenotypesSurveying the medical, surgical, and pathological aspects of endocrine therapy, as well as future research opportunities, Endocrine Therapy in Breast Cancer is a concise and in-depth manual for medical, surgical, and radiation oncologists; endocrinologists; gynecologists; obstetricians; pharmacologists; family physicians; reproductive biologists; epidemiologists; and medical school students.